Ghrelin-reactive immunoglobulins and anxiety, depression and stress-induced cortisol response in adolescents. The TRAILS study.
Identifieur interne : 000152 ( France/Analysis ); précédent : 000151; suivant : 000153Ghrelin-reactive immunoglobulins and anxiety, depression and stress-induced cortisol response in adolescents. The TRAILS study.
Auteurs : Marie François [France] ; Johanna M. Schaefer [Pays-Bas] ; Christine Bole-Feysot [France] ; Pierre Déchelotte [France] ; Frank C. Verhulst [Pays-Bas] ; Sergueï O. Fetissov [France]Source :
- Progress in neuro-psychopharmacology & biological psychiatry [ 1878-4216 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- immunologie : Ghréline, Grippe humaine, Simplexvirus.
- métabolisme : Anxiété, Dépression, Hydrocortisone, Salive, Stress psychologique.
- sang : Immunoglobulines.
- Adolescent, Facteurs sexuels, Femelle, Humains, Mâle.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Immunoglobulins.
- chemical , immunology : Ghrelin.
- immunology : Influenza, Human, Simplexvirus.
- metabolism : Anxiety, Depression, Hydrocortisone, Saliva, Stress, Psychological.
- Adolescent, Female, Humans, Male, Sex Factors.
Abstract
Ghrelin, a hunger hormone, has been implicated in the regulation of stress-response, anxiety and depression. Ghrelin-reactive immunoglobulins (Ig) were recently identified in healthy and obese humans showing abilities to increase ghrelin's stability and orexigenic effects. Here we studied if ghrelin-reactive Ig are associated with anxiety and depression and with the stress-induced cortisol response in a general population of adolescents. Furthermore, to test the possible infectious origin of ghrelin-reactive Ig, their levels were compared with serum IgG against common viruses.
DOI: 10.1016/j.pnpbp.2014.12.011
PubMed: 25562566
Affiliations:
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pubmed:25562566Le document en format XML
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<term>Anxiety (metabolism)</term>
<term>Depression (metabolism)</term>
<term>Female</term>
<term>Ghrelin (immunology)</term>
<term>Humans</term>
<term>Hydrocortisone (metabolism)</term>
<term>Immunoglobulins (blood)</term>
<term>Influenza, Human (immunology)</term>
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<term>Humains</term>
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<term>Immunoglobulines (sang)</term>
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<term>Salive (métabolisme)</term>
<term>Simplexvirus (immunologie)</term>
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<front><div type="abstract" xml:lang="en">Ghrelin, a hunger hormone, has been implicated in the regulation of stress-response, anxiety and depression. Ghrelin-reactive immunoglobulins (Ig) were recently identified in healthy and obese humans showing abilities to increase ghrelin's stability and orexigenic effects. Here we studied if ghrelin-reactive Ig are associated with anxiety and depression and with the stress-induced cortisol response in a general population of adolescents. Furthermore, to test the possible infectious origin of ghrelin-reactive Ig, their levels were compared with serum IgG against common viruses.</div>
</front>
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<name sortKey="Fetissov, Serguei O" sort="Fetissov, Serguei O" uniqKey="Fetissov S" first="Sergueï O" last="Fetissov">Sergueï O. Fetissov</name>
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<country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Schaefer, Johanna M" sort="Schaefer, Johanna M" uniqKey="Schaefer J" first="Johanna M" last="Schaefer">Johanna M. Schaefer</name>
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